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WJPPS SEPTEMBER ISSUE PUBLISHED

SEPTEMBER 2020 Issue has been successfully launched on 1 September 2020.

Abstract

SIMULTANEOUS ESTIMATION OF ACECLOFENAC AND PARACETAMOL ORODISPERSIBLE TABLETS BY SPECTROPHOTOMETRIC METHOD

*Manasa Gururaj¹, Snehalatha¹, Yogananda R¹, H.S Basavaraja², Santhose Varma¹, Bharathi D.R³

¹PG Dept. of Pharmaceutics, S.J.M College of Pharmacy, Chitradurga, Karnataka, India.

²PG Dept. of Pharmachemistry, S.J.M College of Pharmacy, Chitradurga, Karnataka, India.

³PG Dept. of Pharmacology, S.J.M College of Pharmacy, Chitradurga, Karnataka, India.

ABSTRACT

Here an attempt has been made to develop a simple, economic, sensitive and reproducible spectrophotometric method for quantitative estimation of Aceclofenac (ACE) and Paracetamol (PARA) from bulk drug and in pharmaceutical formulations. In this spectroscopic method, simultaneous estimation of ACE and PARA at max 274nm and 243.5nm respectively by utilizing spectrum mode of analysis in U.V visible spectrometer. The method employing simultaneous equation is very simple method and can be employed for routine analysis of Aceclofenac and Paracetamol. The proposed method is highly sensitive and successfully applied for the analysis of Aceclofenac and Paracetamol in tablet formulation.

Keywords: Aceclofenac (ACE), Paracetamol (PARA).

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