Abstract

THE DEVELOPMENT OF A TECHNOLOGY OF A MEDICINAL CREAM, CONTAINING RHIZOMES OF A WHITE CINQUEFOIL PLANT (POTENTILLA ALBA L.)

Chelidze N. A., Yavich P. A.*,  Churadze L. I. and Kakhetelidze M. B.

ABSTRACT

The rhizome of the plant Potentilla white (Potentilla alba L.) grows quite widely in Georgia. Biologically active compounds, obtained from rhizomes, are known to have anti-inflammatory, hemostatic, astringent, restorative, anti-burn and antimicrobial effects. This article presents data on the development of a technology for producing a natural medicinal cream ,using rhizomes of a white potentilla plant, by mixing a cream or ointment base, containing both water and oil, with finely ground vegetable raw materials. In this case it is possible to obtain directly in the base, without using additional procedures, an extract from a plant, containing in a certain amount both water-soluble and fat -soluble biologically active substances. The advantage of keeping the raw material in the base is the possibility of hydrolysis of macromolecular compounds to the ones of the lower molecular mass . That will provide the higher adsorption of the biologically active substance. Taking into the account that we use the finely ground plant material powder with a size of the particles of less than 0.1-0.25 mm , when applying the obtained product to the skin , the skin extracts to a certain extent (depending on the structure and characteristics of the skin of a particular patient) an additional amount of biologically active substances.

Keywords: White cinquefoil (Potentilla alba L.), extraction, creams.