WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL TABLETS OF METRONIDAZOLE

Korem Raju*, K. Manasa, K. Ramyameena, J. Amulya Kiron, Ch. Anusha and S. Lavanya

ABSTRACT

Mucoadhesive buccal drug delivery offers a direct delivery of drug to buccal cavity by means of drug –polymer interaction with avoiding pre systemic metabolism. In present study is to design and develop metronidazole buccal tablets by direct compression method. Nine formulatons were prepared by using different polymers such as HPMCK100, PVPK30, carbopol934 and ethyl cellulose as a backing layer and along with suitable excipients. Various pre and post compression evaluation parameters evaluated and concluded that all tests were passed and with in the I.P limits. From all formulation F8 formulation shows controlled and complete release of Metronidazole over a period of 7 hours containing polymer as PVPK30 and Carbopol934 and shows 99.07% drug release.

Keywords: CP = Carbopol 934P, PVP = Poly vinyl pyrolidine, HPMC = Hydroxy propyl methyl cellulose, EC =Ethyl cellulose, % == Percentage, F8 = Formulation no 8, I.P = Indian pharmacopoeia.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More