Abstract

A COMPARATIVE STUDY OF EPIDURAL ROPIVACAINE 0.75% ALONE WITH ROPIVACAINE PLUS CLONIDINE AND ROPIVACAINE PLUS DEXMEDETOMIDINE FOR LOWER ABDOMINAL AND LOWER LIMB SURGERIES

Manjunath Thimmappa*, Ravi Madhusudhana, Somasekharam Potli, Dinesh Karthick.

ABSTRACT

Aims and Objectives:To compare epidural ropivacaine 0.75% alone and Ropivacaine 0.75% with alpha 2 agonists. Variables like block characteristics, hemodynamics, sensory and motor recovery, side effects are analysed. Materials: With Institutional ethical committee clearance, clinical Study conducted at R.L.J.H, Kolar. After obtaining informed written consent,90 patients of(American Society of Anaesthesiologists) ASA Grade I and II in age group 18 to 55 years, of either sex, posted for elective lower abdominal and lower-limb surgeries were selected. Methods:Patients were randomly allocated into 3 groups of 30 each.Epidural block was administered.Patients in group“R” received 19ml 0.75% ropivacaine with 1ml of normal saline. Group “RC” patients received 19ml 0.75% ropivacaine with 75microgram(mcg) clonidine while patients in group “RD” received 19ml0.75% ropivacaine with 75 mcg dexmedetomidine. Block characteristics like onset of analgesia, maximum level of sensory blockade, complete motor blockade, hemodynamics, time to two segment regression, time for rescue analgesia, time to complete motor recovery, side effects were analysed. Results: Results showed that onset of blockade is faster when additives are added like clonidine and dexmedetomidine. Time for two segment regression was 30-35minutes earlier in Group “RC”.(R

Keywords: epidural anaesthesia, ropivacaine, clonidine, dexmedetomidine.