Abstract

CLINICAL PROFILE OF PATIENTS ADMITTED WITH SUPRAVENTRICULAR TACHYCARDIA AND REVERSION TO NORMAL SINUS RHYTHM WITH ANTIARRHYTHMICS

Aleena M. Abraham*, Anshy Ansen, Resni Reji, Dr. Leena P. N., Dr. Cherian Koshy, Dr. Santosh M. Mathews

ABSTRACT

The objective of this work is to assess the clinical profile of patients admitted with Supraventricular tachycardia and reversion to normal sinus rhythm using antiarrhythmics. A prospective observational study was conducted on 45 patients with Supraventricular Tachycardia and patients were divided into Adenosine, Verapamil and Amiodarone groups based on the dose of the drug that caused successful reversion such as adenosine 6mg, 12mg; verapamil 2.5mg, 5mg; and amiodarone 150mg; and then reversion rates were calculated. On evaluation of the clinical profile of patients it was found that there were no significant differences in mean age, blood pressure and heart rates between the drug groups and hypertension was the most occurred comorbid condition. Secondly it was found that there was equal reversion rates with adenosine 6mg and 12mg(35.6%), verapamil 2.5mg had a reversion rate of 6.6%,verapamil 5mg 13.3% and adenosine 150mg 8.8%(p value is < 0.05). However the frequency of recurrence in adenosine groups were found to be higher when compared to verapamil and amiodarone with zero recurrence rate. Statistical analysis was conducted using Statistical Packages for Social Sciences software. This study showed that though verapamil is equally effective as adenosine in reverting back Supraventricular tachycardia, it cannot be used as the first line drug of choice. Amiodarone is also used as an alternative for Supraventricular tachycardia in cases where patients have Left Ventricular dysfunction and increased breathlessness but its use as a first line drug is limited due to its increased side effects. Thus adenosine is preferred drug of choice.

Keywords: Supraventricular tachycardia, adenosine, amiodarone, verapamil, reversion.