Abstract

ANEMIA IN CHILDREN: A MINI REVIEW

Hanif Azad*, Chetan Kumar Joshi, Mukesh Sharma and Asif Anas

ABSTRACT

The term anemia is defined as decline or below the normal range of red blood cells in circulating blood. Anemia is initial condition that by some estimate is not clearly predictable and treated. Primary effect of anemia is the reduction of oxygen concentration on blood as well as in tissue and secondary it might be responsible for the development of many other coexisting diseases. It can be preliminary diagnosed with symptoms include: weakness, headache, chest pain, pallor/jaundice, fatigue, dyspnoea, light-headedness, tachycardia/palpitations, claudication, and cold distal extremities. WHO suggested in 2010, if Hb level is found less than 12g/dl in female having mensuration while if found 13 g/dl in male of all age and female of after menopause are considered as anemic. It is observed that approximately two million red blood cells (RBCs) were formed in every second in a healthy individual by the process of coordination that start with multipotent hematopoietic stem and progenitor cells (HSPCs). The erythropoiesis is a model of this developmental pathway. It was reported that multipotent and lineage-committed progenitors might be responsible for the production of differentiated blood cells under study state conditions on the place of hematopoietic stem cells (HSCs).

Keywords: Anemia, RBCs, HSPCs, diseases, blood.