Abstract

A REVIEW ON STEM CELL TREATMENT FOR ISCHEMIC STROKE

Sukanya Challagundla*, Sandhya Mylipilli, Prathibha Natta and Padmalatha Kantamneni

ABSTRACT

Stroke sometimes reffered to as a brain injury caused by a sudden interruption in the blood supply of the brain. Stroke occurs when part of the brain does not receives the needed blood flow for one or two reasons either the blood supply to part of the brain is suddenly interrupted, or because a blood vessel in the brain ruptures and blood invades the surrounding areas these are the reasons for the occurrence of stroke. Central information-processing organ of the body is brain and it is responsible for the control of multiple complex functions. The brain cells start to die (cerebral infarction) leading to brain damage without the blood supply. Approximately two million brain cells die every minute during a stroke which increases the risk damage to brain, disability and death. According to the type of stroke suffered, the part of the brain affected, and the size of the damaged area the level of disability from patient to patient varies .Various alternative approaches including the use of ESCs, MSCs, NSC, and iPSCs have been tried in hopes of improving the neuronal and functional impairment that usually follows a stroke insult. Stem cell therapy significantly increase neurological functions and quality of life, but more investigation is required to provide evidence to support clinical application of stem cell transplantation.

Keywords: Ischemic stroke, types of stroke, stem cell treatment.