Abstract

A REVIEW ON NANO-BUBBLES

G. Sumalatha*, Dr. M. Sudhakar and D. Prasad

ABSTRACT

Nanobubbles, for ultrasonic targeted which have the potential imaging and treatment in tumors, have been a research focus in recent years.however, the prepared uniformly sized nanobubbles either undergo post-formulation manipulation, such as centrifugation, after the mixture of microbubbles.nanobubbles from the optimal phospholipid film thickness exhibited optimal physical characteristics, such as uniform bubble size, good stability and low toxicity.the optimal phospholipid film thickness canlead to nanobubbles that are effective for tumor imaging. Nanobubbles (NBs) opened a new field of ultrasound imaging. There is still no practical method to control the diameter of bubbles. The size of resulting NBs increased with the decrease in amount of silicon hybrid lipids, indicating the diameter of NBs can be regulated through modulating the ratio of silicon hybridlipids in the bubble shell. Nanobubbles are tiny spherical cap-shapedbubbles, and have several unique physical and mechanical. Their peculiar characteristics have led to many applications in the various fields of science and technology, including industrial, biological, and medical fields.Range of particle size of resulting NBs is between 523.02 ± 46.45 to 857.18 ± 82.90, smaller than the conventional microbubbles. NBs in future applications including contrast-enhanced imaging and drug/gene delivery.

Keywords: nanobubbles, Silicon hybrid, Nano bubble stability.