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Abstract

PHYTOCHEMICAL AND ANTIBACTERIAL ANALYSIS OF KEDROSTIS FOETIDISSIMA AGAINST A FEW RESPIRATORY ISOLATES

Sharly Elgal N, Arulkumar L, *Jasmine R

ABSTRACT

Treatment of respiratory infections caused by resistant bacteria has become very difficult, since they are resistant to many antibiotics. This limits therapeutic options. Therefore, alternative methods of treatment are sought after. Many infectious diseases have been known to be treated with herbal remedies throughout the history of mankind. Natural products, either as pure compounds or as standardized plant extracts, provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. The use of plant extracts and phytochemicals, both with known antimicrobial properties, can be of great significance in therapeutic treatments. Hence, studies pertaining to the use of plants, as therapeutic agents should be emphasized, especially those lated to the control of antibiotic resistant microbes. Medicinal plants have been found to possess certain active principles useful for treating diseases. In this study, we have evaluated the different extracts of Kedrostis foetidissima against drug resistant human pathogens. The extracts were tested for antibacterial activity by disc diffusion method and the dosage was determined by broth dilution method. Results of zones of inhibition and MIC values are significant and hence it can be concluded that Kedrostis foetidissima can be a potential source of therapeutic drug. Phytochemical analysis has revealed the active components present which could attribute to the reported activity. Further investigations to discover natural compounds that may serve as lead compounds for drug development are under progress.

Keywords: Kedrostis foetidissima ; antibacterial; Minimal Inhibitory Concentration.


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