PHYTOCHEMICAL AND ANTIBACTERIAL ANALYSIS OF KEDROSTIS FOETIDISSIMA AGAINST A FEW RESPIRATORY ISOLATES
Sharly Elgal N, Arulkumar L, *Jasmine R
ABSTRACT
Treatment of respiratory infections caused by resistant bacteria has
become very difficult, since they are resistant to many antibiotics. This
limits therapeutic options. Therefore, alternative methods of treatment
are sought after. Many infectious diseases have been known to be
treated with herbal remedies throughout the history of mankind.
Natural products, either as pure compounds or as standardized plant
extracts, provide unlimited opportunities for new drug leads because of
the unmatched availability of chemical diversity. The use of plant
extracts and phytochemicals, both with known antimicrobial
properties, can be of great significance in therapeutic treatments.
Hence, studies pertaining to the use of plants, as therapeutic agents
should be emphasized, especially those lated to the control of antibiotic resistant microbes.
Medicinal plants have been found to possess certain active principles useful for treating
diseases. In this study, we have evaluated the different extracts of Kedrostis foetidissima
against drug resistant human pathogens. The extracts were tested for antibacterial activity by
disc diffusion method and the dosage was determined by broth dilution method. Results of
zones of inhibition and MIC values are significant and hence it can be concluded that
Kedrostis foetidissima can be a potential source of therapeutic drug. Phytochemical analysis
has revealed the active components present which could attribute to the reported activity.
Further investigations to discover natural compounds that may serve as lead compounds for
drug development are under progress.
Keywords: Kedrostis foetidissima ; antibacterial; Minimal Inhibitory Concentration.
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