Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS: JUNE ISSUE PUBLISHED
  • JUNE 2021 Issue has been successfully launched on 1 June 2021.

Abstract

ROLE OF MEDICAL EXPULSIVE THERAPY IN LOWER URETERAL CALCULUS

Dr. Ashok Saini, *Dr. Mayank Jain and Dr. Anant Kamath

 

ABSTRACT

Introduction: Medical expulsive therapy (MET) has been proven to enhance stone expulsion rate, decrease stone expulsion time for lower ureteric stones. While alpha-blockers are currently recommended monotherapy, corticosteroids are useful adjunct in MET. Objectives: To determine efficacy and safety of MET by evaluating the role of corticosteroid Deflazacort in combination with alpha blocker Tamsulosin in medical management of symptomatic lower ureteric stones. Methods: 105 patients of symptomatic lower ureteric calculus of 5mm to 10 mm in diameter were included in the study. Patients were divided in to 3 groups; Group A has 35 patients receiving only analgesics as control group, Group B had 35 patients receiving Tamsulosin and Group C 35 patients who received Tamsulosin and Deflazacort combination. The maxmimum treatment duration was of 28 days. Results: The stone expulsion rate was 17/35(48.30%), 26/35(74.60%), 28/35(80%) in groups A,B and C respectively. Stone expulsion rate was significant between groups A&B, A&C but not between group B& C. The mean expulsion time was significantly less in group C compare to group A & B. Conclusion: MET with Tamsulosin and Deflazocort has higher stone expulsion rate compared to tamsulosin or placebo alone.The combination also has faster stone expulsion and it proved to be safe and effective.

Keywords: MET-Medical expulsive therapy, Alpha blocker Tamsulosin, Deflazacort, Lower ureteric calculus.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More