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Abstract

EFFECT OF MORINGA OLEIFERA LEAF EXTRACTS ON SERUM LEVELS OF ZINC, COPPER AND SELENIUM IN ALBINO RATS

Adeniran Samuel Atiba, Dolapo Pius Oparinde, Bisade Patience Taiwo, Nurudeen Ola Bello*, Joel Olufunminiyi Akande and Temitope Adeola Niran-Atiba

 

ABSTRACT

Trace elements play versatile roles in human body such as provision of anti-oxidant defense. Eradication of nutritional deficiencies among women and children on a global scale are needed to ensure improved quality of life for the next generation of citizens. Moringa oleifera trees have been used to combat malnutrition, especially among infants and nursing mothers. This study determined the effect of Moringa oleifera leaf feeding on serum levels of zinc, copper and selenium in albino rats. Seventy albino rats were used for the experiment (40 tests and 30 controls). The test group was fed with growers mash mixed with Moringa oleifera leaf, while the control was fed with just growers mash for 5weeks. At the end of the experiment, the animals were sacrificed and their blood was used to determine serum trace elements (copper, zinc and selenium) using Atomic Absorption Spectrophotometry. Result Showed a significant increase in the serum levels of these trace elements compared with the control (P<0.05). There was also a strong positive correlation between zinc and copper (r=.786**), copper and selenium (r=.931**) and zinc and selenium (r=.671**) (P<0.01). This study establishes a strong relationship between Moringa oleifera leaf feeding and increased serum levels of trace elements measured in the test group. This suggests that Moringa oleifera leaves contain these selected trace elements.

Keywords: Moringa Oleifera, Trace Element, Copper, Zinc, Selenium.


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