Photo Gallery



News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • JULY 2021 Issue has been successfully launched on 1 July 2021.



Bhandari Neeraj* and Dr. Gupta Rajesh



The present investigation involves formulation of Acelofenac topical gel having by modification of the “cold dispersion” method described by Schmolka. Aceclofenac has been shown to have potent analgesic and anti-inflammatory activities, similar to indomethacin and diclofenac and due to its preferential cox-2 blockade, it has better safety than conventional NSAIDs with respect to adverse effects on gastrointestinal and cardiovascular system. Aceclofenac is used in treatment of osteoarthritis, rheumatoid arthritis, acute lumbago, and dental pain condition. The formulation of Acelofenac topical gel was prepared using HPMC, Carbopol 974 P and Sodium CMC in three different batches. Aceclofenac topical gels are prepared in this study. Studies showed that drug release was decrease with increase in gelling agent concentration because polymer concentration increases, viscosity increases. The best release pattern of drug was observed F15- Poloxamer-407. So, then release pattern order Poloxamer-407> HPMC>Carbopol-940> Carbopol-934. On the basis of physical parameters and release pattern F2, F6, F11, F15 selected as best formulations. Further stability of selected formulation had been done on different temperature such as on 4°c, 25°c and 37°c for 3 months. There were no significant changes in the viscosity, and physical appearance of the gel. After storing at different temperature conditions for three months.

Keywords: COX- 2, Lumbago. Rheumatoid Arthritis.

[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More