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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

Call for Paper

WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS: MAY ISSUE PUBLISHED

May Issue has been successfully launched on 1 May 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

CYCLOSPORIN INDUCED RENAL DAMAGE: A CASE REPORT

Dona Johnson*, Arshad K. T., Aneeta Jacob, Amala T. A., Sanjana Suresh

ABSTRACT

Cyclosporin is lipophilic polypeptide having 11 aminoacids. It have a unique immunosuppressive activity. It mainly acts on lymphocytes particularly helper T cells to produce suppression in cell mediated immunity. Their action is mainly by forming complex with cyclophilin in the cytoplasm. This complex then binds to calcineurin which is a calcium and calmodulin dependent phospholase. This leads to the activation or translocation of a nuclear factor, which binds and transcribe the interlukin 2 gene. Cyclosporins also inhibit other cytokines including interferones and interlukins.[1]

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