Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS AUGUST ISSUE PUBLISHED
  • AUGUST 2020 Issue has been successfully launched on 1 August 2020.

Abstract

ADVERSE EFFECT OF DRUG (FLORFENICOL) IN BROILER CHICKENS INFECTED WITH ESCHERICHIA COLI.

Ashraf A. A. El-Komy, Enas A. H. Farag and Ahmed Rady*

ABSTRACT

This study was carried out to investigate the effects of chemical antibacterial (florfenicol) (1ml /10 kg. body weight orally for 5 successive days) to be used in prevention of colibacillosis caused by Escherichia coli infections in poultry farms and their effect on some of liver and kidney functions. The recorded results elicited a significant increase in AST, and ALT levels and significant decrease in total protein and albumin levels in chicken infected and treated with florfenicol At 6 and 10 days post treatment with the therapeutic dose of florfenicol (1ml /10 kg. body weight orally for 5 successive days) on uric acid and creatinine level of healthy and experimentally infected chickens with E.coli. group infected treated with florfenicol showed a significant increase in serum uric acid and creatinine level when compared with non infected non treated (control group). From this study we can concluded florfenicol, increase the hepatorenel toxic effect of in E.coli infected broiler chickens. And we should seek for alternative antibacterial in broilers to avoid side effects of chemical antibacterial drugs such as florfenicol residues and resistance.

Keywords: Hepatorenal toxicity, florfenicol. E.coli.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More