Abstract

EVALUVATION OF INVITRO ANTIDIABETIC ACTIVITY OF TOTAL ALCOHOLIC LEAF EXTRACT OF MORINDA CITRIFOLIA

Alan Jacob*, Ragesh T., Mohammed Shahjad B. A., Pradija Sasidharan and Saliha P.A.S.

ABSTRACT

Morinda citrifolia, L. popularly known as Indian Noni or Indian mulberry is an evergreen small tree. It belongs to the family Rubiaceae. Noni is one of the important traditional folk medicinal plant that have been used for over 2000 years in Polynesia. It has been reported to have a broad range of therapeutic and nutritional value. All the plant parts are used in the treatment of various diseases and disorders. The fruit is important because of its wide range of therapeutic potentials such as anti-bacterial, anti- viral, anti-tumor, anti-helminthes, analgesic, hypertensive, anti-inflammatory and immune enhancing effects. The total alcoholic extract of Morinda citrifolia leaves show significant in vitro antidiabetic activity when compared with the standard acarbose. The in vitro antidiabetic activity was carried out by using α-amylase inhibition method.

Keywords: Morinda citrifolia, ?-amylase inhibition.