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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

Call for Paper

WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

IN VIVO AND IN-VITRO EVALUATION OF TUMOR INHIBITION & CYTOTOXICITY ACTIVITY OF AQUEOUS EXTRACT OF ONION (ALLIUM CEPA) & GARLIC (ALLIUM SATIVUM)

Yogita Temak*, Pravin Cholke, Lokhande Jayshri, Kunjir Yojana

ABSTRACT

The present study was aimed to investigate the effects of aqueous extract of four different varieties of Allium cepa (Onion) & Allium sativum (Garlic) on B16F10 Melanoma cell population by ex-vivo. For cytotoxicity assay, cellular micronucleus, apoptotic assay and cell viability assay were followed. Our results showed significant activity of garlic and onion as cytoprotective agents of normal cells and cytotoxicity agents for tumor cells. A significant decrease in Melanoma B16F10 cell population by crude extract was observed. Therefore, Allium cepa & Allium sativum might be a candidate for naturally healing the tumor.

Keywords: Cytotoxicity, Melanoma, Onion (Allium cepa) & Garlic (Allium sativum).

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