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Abstract

A REVIEW ON VARIOUS METHODOLOGIES FOR THE SIMULTANIOUS ESTIMATION OF LEVOCETIRIZINE HYDROCHLORIDE AND MONTELUKAST SODIUM IN PHARMACEUTICAL DOSAGE FORM

Amrita Chourasia*, Sandeep Sahu, Meghna Amrita Singh , Sushmita Mishra

ABSTRACT

The Levocetirizine Hydrochloride and Montelukast Sodium Combination therapy is a more effective strategy than mono therapy in the treatment of persistent allergic rhinitis. The pharmacokinetics of Levocetirizine Hydrochloride and Montelukast Sodium has been extensively investigated in human subjects. There are some analytical methods in the literature for the analysis of both compounds in the pharmaceutical preparations. In this work, we have recompiled these methods with the aim to present the different options for the simultaneous estimation of Levocetirizine Hydrochloride and Montelukast Sodium determination in pharmaceutical dosage form.

Keywords: Levocetirizine and Montelukast , HPLC, Method Development.


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