WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

SPHERICAL CRYSTALLIZATION –A NOVEL DRUG DELIVERY SYSTEM

Mohan R. S.*, Karad P. B., Gore S. J., Tagad R. R.

ABSTRACT

Spherical crystallization is the novel agglomerated technique that can directly transform the fine crystals produced in the crystallization process into a spherical shape. It is the particle engineering technique by which crystallization and agglomeration can be carried out simultaneously in one step to transform crystals directly into compacted spherical form. This technique of particle design of drugs has emerged as one the areas of active research currently of interest in pharmaceutical manufacturing and recently came into the forefront of interest or gained interest due to the fact that crystal habit can be modified during crystallization process which would result in better micrometric properties like particle size those can enhance the flow ability of the powder drug and prepared spherical crystals can be compress directly without performing granulation, drying and so many steps those are require in wet granulation and in dry granulation process of tablet manufacturing. Spherical crystallization of drugs is the process of obtaining larger particles by agglomeration during crystallization. The most common techniques used to obtain such particles are spherical agglomeration and quasi-emulsion solvent diffusion. Ammonia diffusion systems and crystalloid- co-agglomeration are extensions of these techniques.

Keywords: Spherical crystallization, Drug, Techniques, agglomeration, solvent diffusion, improved particle properties.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More