Abstract

PATIENT AND DRUG-RELATED RISK FACTORS FOR INTENSIVE CARE UNIT ACQUIRED INFECTIONS IN DIFFERENT GOVERNMENTAL HOSPITALS IN KHARTOUM STATE

Dr. Tarig Osman*, Eltayeb Mohamed, Kamal Elhag and Ahmed Abu Salab

ABSTRACT

Hospital-acquired infection is a serious problem in the ICU. Infection in ICU is associated with increased mortality, morbidity and carries a substantial economic burden. Objectives: This study was carried out to determine patient and drug-related risk factors for intensive care unit acquired infections in different governmental hospitals in Khartoum State. Method: This is a prospective observational cross-sectional, case-finding, follow up ICU-based study. The study was conducted in intensive care units of nine governmental hospitals in Khartoum state, during the period from August 2016 to January 2017. 1230 patients were enrolled in this study. Data collected using predesigned data collection sheet. Then data were analyzed using SPSS. Results: The majority (54%) of patient population fell in age above 46 years, Males outnumbered females. When the chi-square test was used, significant (p>0.05) relationships were found between the development of ICU-acquired infection and patient related factors (non-modifiable), which are age, past medical history, cause of admission. However, there is no significant association between ICU infection and gender. Additionally, chi-square test show significant (p>0.05) relationships between ICU-acquired infection and drug use of proton pump inhibitors, immunosuppressant and prophylactic antibiotics. Conclusion: The findings of this study revealed that patient and drug related factors are considered as significant risk factors to develop ICU-acquired infections. The healthcare providers should give additional care for patients with such risk factors, since ICU-acquired infections is associated with higher mortality and morbidity. Key words: Risk factors, Intensive care unit, Infections.

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