Abstract

CHANGES IN SOME COAGULATION PARAMETERS AMONG DIABETIC PATIENTS IN MICHAEL OKPARA UNIVERSITY OF AGRICULTURE, UMUDIKE, ABIA STATE, NIGERIA.

Obeagu Emmanue Ifeanyi*, Obarezi Henry Chukwuemeka, Aloh Godwin Sunday, Emelike Chinedum Uche

ABSTRACT

Diabetes mellitus or diabetes is a metabolic disorder characterised with chronic hyperglycemia which results in plyuria,poydipsia and polyphagia.It has high level of morbidity and mortality in Nigeria.Type 2 diabetes mellitus is common here in Michael Okpara University of Agriculture ,Umudike,Abia State,Nigeria.This could be as a result of their lifestyle.The study was carried out using 30 confirmed type 2 diabetics(20 male,10 female) with average age of 48 years and 30 nondiabetics( 20 male,10 female) with average age of 47years attending University Health Services Department of the University.The study showed significant prolonged time in mean value of APTT and increased weight of fibrinogen in the diabetics(P<0.05) relative to the non-diabetics and no significant change(P>0.05) in TT and PT. The prolonged time of APTT could be as a result of inhibitors of intrinsic system.The study is aimed at finding out any significant change and how to manage the patient to help in the improvement of health status of the type 2 diabetics.

Keywords: Coagulation study,Intrinsic system,Type 2 diabetes mellitus patients.