CHANGES IN SOME COAGULATION PARAMETERS AMONG DIABETIC PATIENTS IN MICHAEL OKPARA UNIVERSITY OF AGRICULTURE, UMUDIKE, ABIA STATE, NIGERIA.
Obeagu Emmanue Ifeanyi*, Obarezi Henry Chukwuemeka, Aloh Godwin Sunday,
Emelike Chinedum Uche
ABSTRACT
Diabetes mellitus or diabetes is a metabolic disorder characterised
with chronic hyperglycemia which results in plyuria,poydipsia and
polyphagia.It has high level of morbidity and mortality in Nigeria.Type
2 diabetes mellitus is common here in Michael Okpara University of
Agriculture ,Umudike,Abia State,Nigeria.This could be as a result of
their lifestyle.The study was carried out using 30 confirmed type 2
diabetics(20 male,10 female) with average age of 48 years and 30 nondiabetics(
20 male,10 female) with average age of 47years attending
University Health Services Department of the University.The study
showed significant prolonged time in mean value of APTT and
increased weight of fibrinogen in the diabetics(P<0.05) relative to the
non-diabetics and no significant change(P>0.05) in TT and PT. The
prolonged time of APTT could be as a result of inhibitors of intrinsic system.The study is
aimed at finding out any significant change and how to manage the patient to help in the
improvement of health status of the type 2 diabetics.
Keywords: Coagulation study,Intrinsic system,Type 2 diabetes mellitus patients.
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