Abstract

A REVIEW ON LOCAL ANEASTHETIC MUCOADHESIVE TABLETS

*Goswami Raksha, Gupta Durgesh Kumari, Shrivastava Darshana

ABSTRACT

Today, drug delivery systems designed with the aim to improve patient compliance and convenience is more important than ever. Therefore huge work is going on to develop novel dosage forms to satisfy increased patient demands of more convenient dosage forms. Oral mucosal delivery offers a convenient way of dosing medication, not only to special populations with swallowing difficulties, but also to the general population. Mucoadhesive dosage forms provide prolonged contact time at the site of attachment, having high patient compliance and are economic as compare to other dosage forms. The use of mucoadhesive polymers has made this delivery system of controlled release application. Local anaesthesia remains the foundation of pain control in dentistry. Local anaesthetics remain the safest and most effective drugs in medicine and dentistry to relieve intraoperative and postoperative pain. The amide local anaesthetic agents currently available in dentistry are extremely safe and effective. The availability of various formulations of lidocaine, mepivacaine, prilocaine, articaine, and bupivacaine permits a practitioner to select agents that can meet treatment requirements. The safety and efficacy of current systems can be improved if their delivery rate, biodegradation, and site-specific targeting can be predicted, monitored, and controlled.

Keywords: Mucoadhesive, Local anaesthetics, Controlled drug release, Polymers, Biodegradation, Intraoperative.