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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2025 Issue has been successfully launched on 1 NOVEMBER 2025.

Abstract

METHOD DEVELOPMENT AND VALIDATION FOR AMLODIPINE BESYLATE AND CARVEDILOL IN COMBINE PHARMACEUTICAL DOSAGE FORMS BY RP-HPLC

P. Prashanthi* and M. Srinivas

ABSTRACT

A new method was established for simultaneous estimation of a Amlodipine Besylate and Carvedilol by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Amlodipine Besylate and Carvedilol by using Inertsil -ODS C18(250 x 4.6 mm, 5μ), flow is 1.0 ml/min, mobile phase ratio was Phosphate buffer and Methanol (30:70), detection wave length was 254 nm. Chromatogram observed at RT’s of 3.661min to Amlodipine Besylate and 6.453min to Carvedilol.

Keywords: Amlodipine Besylate and Carvedilol, RP-HPLC, Acetonitrile.

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