Abstract

A NOVEL POTENT MUCO- BIOADHESANT POLYMER FROM THE SEEDS OF RICINUS COMMUNIS

Abhijeet Ojha*, N.V. Satheesh Madhav

ABSTRACT

The aim of our research work was to isolate a biomaterial from the seeds of Ricinus communis and evaluate its mucoadhesivity as well as mucoretaintability. The biomaterial was isolated from the seeds of Ricinus communis by an economical process. It was subjected to various physico-chemical tests as well as spectral analyses like IR, 1H NMR, DSC, SEM and elemental analysis. The mucoadhesivity of biomaterial was screened by shear stress method and rotating basket method. Further its mucoretaintability was determined by MS mucoretaintability apparatus. The biomaterial exhibited inbuilt mucoadhesivity and mucoretaintability, so it can be used as a novel excipient for transmucosal drug delivery.

Keywords: Mucosal drug delivery, labial mucosa, intestinal mucosa, Ricinus communis.