Photo Gallery



News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • MAY 2021 Issue has been successfully launched on 1 May 2021.



Reshma R. Patil. *, Pranita T.Gaikwad, M.A. Bhutkar


Purpose: The objective of this study is to test new formulations, regarding modified release tablets containing pentoxifylline, obtained by technological modulation of the drug release from tablets. we investigate the effect of combination of hydrophilic and hydrophobic wax polymers. Method: We prepared sustained release granules consisting of a hydrophobic wax and granules consisting of a hydrophilic matrix base using the ordinary granulation method, unlike the film coating method using organic solvents and mixed them at a particular ratio to control the release rate and obtained sustained release tablets of pentoxifylline with a satisfactorily reproducible release rate. Result and conclusion: The drug release from various tablets was analyzed according to release kinetics theories. For the tablet formulation no. 6, the value of exponent (n) of the apparent diffusion mechanism calculated by the Korsmeyer–Peppas model was unlikely to be affected by the paddle rotation speed, and was about 0.659. These results suggested that the drug release mechanism of tablet prepared by mixture of both hydrophilic and hydrophobic wax polymers was not easily changed by physical agitation and probably even by peristaltic movement in the gastrointestinal tract.

Keywords: Pentoxifylline, water soluble, Matrix Tablet, hydrophilic, hydrophobic wax polymers.

[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More