Abstract

STUDY ON IMPACT OF SIDE EFFECTS IN THE MANAGEMENT OF TUBERCULOSIS IN THE RURAL AREAS OF PATHANAMTHITTA DISTRICT, KERALA, INDIA

Alsa Ann George*, Shethal Joju, Sona S. Thomas, Sawmya Sabu

ABSTRACT

Tuberculosis (TB) is caused by bacteria (Mycobacterium tuberculosis) that most often affect the lungs. Tuberculosis (TB) is one of the top 10 causes of death worldwide. Our objective was to identify the impact of side effects in the management of tuberculosis as recorded in the register of TB clinic Kozhencherry during the study period. Our study was a retrospective study and a sample size of 200 patient who were diagnosed with Tuberculosis and undergone treatment and on treatment were used for the study. The salient findings of the study were: (1)The highest reported adverse events are Nausea, vomiting and gastritis which is followed by rashes, (2)Extended or change in therapy have to be done in case of severe adverse events such as liver injury, kidney injury and colour blindness. From this study we were able to find out that 13 patients had to change or extend their therapy due to side effects caused by the drugs however a larger incidence of such situation were reduced by the proper counselling and guidance provided by the senior treatment supervisor. The side effects which caused such situated were found to be liver injury, colour blindness and kidney failure.

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