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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

DEVELOPMENT AND VALIDATION OF A ULTRA PERFORMANCE LIQUID CHROMATOGRAPHIC METHOD FOR ASSAY OF ALFUZOSIN HYDROCHLORIDE IN TABLET FORM

Masma Shaik*, Y. Sunandamma and Chinta Srinivasa Reddy

ABSTRACT

A simple, precise, accurate and specific chromatographic method is developed for for the determination of assay of alfuzosin hydrochloride in tablet form. An ultra-performance liquid chromatography instrument and Inertsil ODS-3, 3.0 x 50 mm, 2μ column were used for determination of alfuzosin hydrochloride. The flow rate of 1.0 mL/min was set with isocratic, the temperature of column compartment maintained at 25°C and Ultra violet detection done at 245nm wavelength. The injection volume was 5 μL. The alfuzosin hydrochloride peaks were eluted at 1.3 minute and total run time was set as about 2 minutes. . The developed method was validated in terms of system suitability, selectivity, linearity, precision, accuracy, and robustness for alfuzosin hydrochloride following the ICH guidelines.

Keywords: Alfuzosin hydrochloride, UPLC, Inertsil ODS-3 column, Method development, Method Validation.

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