Abstract

FORMULATION AND EVALUATION OF PINAVERIUM-COLON TABLETS

*B. Raja Narender and T. Panduraju

ABSTRACT

In the present research work colon formulation of Pinaverium targeted to colon by using various polymers developed. Guar gum, Xanthan gum and Locust bean gum were used as enteric coating polymers. The precompression blend of all formulations was subjected “to various flow property tests and all the formulations were passed the tests. The tablets were coated by using polymers and the coated tablets were subjected to various evaluations techniques. The tablets were passed all the tests. Among all the formulations P4 formulation was found to be optimized as it was retarded the drug release up to 18 hours and showed maximum of 98.73% drug release.

Keywords: Pinaverium, Colon targeted drug delivery system, Guar gum, Locust bean gum.