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Abstract

ANTI FERTILITY EFFECT OF ZIZIPHUS JUJUBA MILL.

Rekha.S *, Chandrashekhara.S,

ABSTRACT

The Petroleum ether extract of Zizyphus jujuba leaves (EAZJ, Rhamnaceae) were evaluated for anti-fertility activity in the adult male mouse. This study was designed to assess the effect of EAZJ on sperm morphology, progressive motility and sperm concentration irreversibly in Wistar rats. Extracts were found to produce significant inhibition of sperm motility and cause reduction in viability of sperm cell. Saponin extract is found to be more active to cause immobilization. From this study, it is evident that Zizyphus jujuba severely affects male animal fertility parameters. It is clear that its antifertility effects are reversible.

Keywords: Ziziphus jujuba Mill, saponin, Antifertility/contraception, Wistar rats.


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