Abstract

“INVESTIGATION OF ACTIVE PHYTOCONSTITUENTS OF LEAVES BIXA ORELLANA EXTRACTS”

Rajmani Mafidar*, Dhananjay, Harish Parmar, Rahul Mathur and Dr. Jagdish Rathi

ABSTRACT

The plant Bixa orellana Linn., its affined to family Bixaceae. Is a small evergreen shrub or bushy tree commonly known “annatto” in English and “Sinduri” in Sanskrit[1], The prickly heart shaped pods contain small reddish-orange seeds. each pod contains approximately 50 seeds. That is native to central, south and north America. This is concluded that methanolic extract and aqueous extract are more prone to positive result rather than oil extract. So that Bixa orellena will show their positive activity on aqueous and alcoholic extract and many constituet found positive. The crude extract of Bixa orellana leaves was subjected to a preliminary phytochemical screening for the presence of steroids, flavonoids, tannins, saponins, alkaloids, glycoside, cumerin, and carbohydrates. Carcinogenesis is a multistep process, and oxidative damage is linked to formation of tumors through several mechanisms. Oxidative stresses induced by free radicals and cause DNA damage, which, when left unrepaired, can lead to base mutation, single and double strand unseat, DNA cross-linking, and chromosomal damage and rearrangement.

Keywords: Bixa orellana, tannins, sindur, methanol.