Abstract

A REVIEW ON FORMULATION TECHNIQUES AND EVALUATION FOR IMMEDIATE RELEASE TABLET

Hitesh Wani* and Chandrakant Pardeshi

ABSTRACT

In recent decades, a variety of pharmaceutical research has been conducted to develop new dosage forms assume quality of life, most of these efforts have been focused on ease of medication. In present research, Pharmaceutical products designed for oral deliverydosage form. Recently Immediate release tablet is the most popular among all delivery system existing today because of its convenience of self-administration, compactness and easy manufacturing and Many patients want to quick onset of action in particular therapeutic condition and consequently immediate release formulation is required. Immediate drug release dosage forms disintegrate rapidly after administration with enhanced rate of dissolution. For the development of immediate release dosage form the basic techniques used, as direct compression, wet granulation, etc. by using a diluents or filler & superdisintegrant, superdisintegrants like Sodium starch glycolate carboxymethylcellulose (Croscarmellose), Cross linked Polyvinylpyrrolidone or crospovidone (Polyplasdone) etc. these superdisintegrants are improved disintegration of tablet after adminstration in stomach. Development of immediate release dosage form is a golden tool for expanding marketplace, they are allows for manufacturer to extend market exclusivity, extending product life cycles and generating opportunity.

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