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Abstract

METHOD DEVELOPMENT OF METFORMIN HYDROCHLORIDE RP-HPLC

Gadipally Saikiran*

ABSTRACT

A simple, specific, accurate and precise Reverse Phase High Performance Liquid Chromatographic method was developed metformin hydrochloride in tablet dosage form on RP Kromasil -ODS C18 using mobile phase as Methanol:orthophosphoric acid (50:50)The flow rate was 1.0 ml/min and effluent was monitored at 270nm. The retention time is 2.3 respectively.

Keywords: metformin hydrochloride Reverse Phase High Performance Liquid Chromatography.


[Full Text Article]

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