Abstract

A REVIEW ON PYRONES, PYRONE DERIVATIVES AND THEIR BIOLOGICAL ACTIVITY

S. Janet Beula*, Dr. R. Suthakaran, Rajaram Das, Laxmidar Sahoo, and J. Muthu Mohammed

ABSTRACT

Pyrones or pyranones an unsaturated six membered ring heterocyclic compound. It contains oxygen atom and ketonic functional group. There are two isomers, denoted as 2-pyrone and 4- pyrone. The structure have offered a high value of diversity that is proven useful for the development of new medicinal drugs and improved potency, less toxicity and good pharmacological activity. Now a days pyrone and its derivatives are used for the treatment of an Anticancer, Antibiotics, Insecticidal, Anticoagulants, Herbicidal and HIVprptease etc. The aim of this review is to provide the recent efforts of scinentists in pharmacological screening of pyrones, importants and synthesis of pyrone derivatives,pharmacological action of pyrones and their biological activity.

Keywords: Pyrones, Anticancer, Antibiotics, Insecticidal, Anticoagulants, Herbicidal and HIVprotease