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*Suchita Dhamane1, Geet Asnani1, Aditi S. Kulkarni1, Vijayashri Khandekar1, Dr. V. I. Hukkeri1

1JSPM’s Jayawantrao Sawant College of Pharmacy & Research, Hadapsar, Pune, Maharashtra, India.


Natural remedies are more acceptable in the belief that they are safer with fewer side effects than the synthetic ones.([1]). Herbal formulations have growing demand in the world market. The present work deals with the development and evaluation of the herbal Antidandruff containing hydro-alcoholic extract of neem leaves (Azadirachta indica). Although various herbal formulations are available in the market, we propose to make use of hydro-alcoholic extract of neem (Azadirachta indica) leaves. The plants have been reported in the literature having good anti-microbial, anti-oxidant and anti-inflammatory activity. Various formulation batches i.e., F1 to F5 were prepared using gelling agent like carbopol 934, in varied concentrations. Prepared formulations (F1 to F5) were evaluated for various parameters like colour, appearance, consistency, washability, pH, spreadability along with antimicrobial efficacy study. Optimized formulation was compared with the marketed preparation. Amongst all the formulation studied batch F3 was found optimum for all the parameter. It is a very good attempt to establish the herbal gel containing hydro-alcoholic extract of neem leaves (Azadirachta indica).

Keywords: Antifungal, Gel, Neem.

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