Abstract

AN OVERVIEW ON ISATINS AND ITS DERIVATIVES

Divya Arora*, Pooja Sharma, Aman Patial, Malvika Rana and Bhandari Neeraj

ABSTRACT

The present review article offers a detailed account on the synthesis of isatin and its derivatives. The isatin moiety displays wide range of biological and pharmacological activities such as anti-tumor, anti-HIV, antiviral, anti-angiogenic, antifungal, anti-Parkinson’s disease, anticonvulsants, etc. It contains the synthesis of substituted isatins, conversion of aniline to isatins, synthesis of new 3-[(5-benzylidene-2- phenyl)-3,5-dihydro-4-H-imidazol-4-one-3-(4-bezoylhydra zono)]- indole-2-ones, etc.

Keywords: Isatin, synthesis, Isatin derivatives.