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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2025 Issue has been successfully launched on 1 NOVEMBER 2025.

Abstract

“SIMULTANEOUS ESTIMATION AND VALIDATION OF DAPAGLIFLOZIN AND SAXAGLIPTIN IN BULK DRUG AND DOSAGE FORM BY RP-HPLC”

*Shraddha Joshi

ABSTRACT

A simple, rapid, precise, accurate and RP-HPLC method has been developed and validated to estimate Saxagliptin and Dapagliflozin in bulk and in dosage form. The samples were eluated Grace C18 (250mm x 4.6ID, Particle size: 5 micron with mobile phase Methanol: water (80:20) at wavelength 225 nm. A good linear response was obtained in the range from 5-25μg/mL of Saxagliptin hydrochloride and 10-50 μg/mL of Dapagliflozin. The method was quantitatively evaluated in terms of linearity, precision, accuracy (recovery), selectivity and robustness as per ICH guideline.

Keywords: RP-HPLC, Saxagliptin, Dapagliflozin.

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