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Abstract

ANTI-TUSSIVE ACTIVITY OF PIPER LONGUM CHURNA

*Sonvale Vaijath1, Pal Surendrakumar1, Chaudhary Vijay1, Mohammed Rageeb Mohammed Usman2, Fakir Saddam Shah2, Patil Tushar 3

1Department of Pharmaceutics, Smt. S. S. Patil College of Pharmacy, Chopda Maharashtra, India.
2Department of Pharmacognosy, Smt. S. S. Patil College of Pharmacy, Chopda Maharashtra, India.
3Department of Pharmacology, Smt. S. S. Patil College of Pharmacy, Chopda Maharashtra, India.

ABSTRACT

The present study is on anti-tussive activity of the macerated extract of piper longum churna by comparison to other marketed preparation as well as reference standard Codeine phosphate using the acetic acid induced cough models in guinea pigs. The standard drug codeine phosphate bought about a reduction of bouts of cough from 15.62 to 1.00.11 (93.60% inhibition), which was significant compared (P<0.01). The percentage inhibition of bouts of cough for in-house formulation ( 92.15% ) was very significant compared to standard as well as other marketed preparation .Thus the present study justifies the traditional claims of piper longum churna in the treatment of cough.

Keywords: Piper longum churna, Ayurvedic formulation, Antitussive activity, Std. Antitussive formulation.


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