REVIEW OF TOPICAL PAIN KILLER GEL
*Priya munshi, D.S.Mohale, A. V. Chandewar
Department of Quality assurance, P. Wadhwani College of Pharmacy, Yavatmal - 445001. India.
ABSTRACT
It is phynyl acitic acid derivative developed as anti-inflammatory
agent. It has nalgesic anti-inflammatory antipyretic like actions like
other NSAIDS. It is recommended in long term treatment of
rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It is
also useful acute mescuskelatal disorder post operative pain and
dysmenorrhoea Diclofenac sodium gel were developed in different
formulations to by employing different grades of polymers such as
Hpmck4m and Crbopol940. There the various Diclofenac gels are
available in market.but the propose gel is formulated with two key
ingredients oleoresin, andl linseed oil contribute to anti-inflammatory
effect. The formulations were evaluated for various physical
parameters, ph spredibility, drug relese excrutability studies drug
released mechanisms.formulation showed maximum drug releaseof
hours and maximum drug. Finally the gel formulations found to be
economical and may overcome the draw backs associated with the drug during its absorption.
Keywords: Diclofenac sodium, Topical Gel, Pain killer.
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