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Abstract

MICROSPHERES A MAGICAL NOVEL DRUG DELIVERY SYSTEM: A REVIEW

*Preeti Agrawal1, Sarlesh Rajput1, Ashish pathak1, Nikhil Shrivastava2, Satyendra Singh Baghel2, Rajendra singh Baghel2

1Department of Pharmaceutics, ShriRam College of Pharmacy, Morena, M.P., India
2Department of Pharmacology, ShriRam College of Pharmacy, Morena, M.P., India

ABSTRACT

Drug delivery systems (DDS) that can precisely control the release rates or target drugs to a specific body site have had an enormous impact on the health care system. So the concept of targeted drug delivery is designed for attempting to concentrate the drug in the tissues of interest while reducing the relative concentration of the medication in the remaining tissues. As a result, drug is localized on the targeted site. Hence, surrounding tissues are not affected by the drug. So, carrier technology offers an intelligent approach for drug delivery by coupling the drug to a carrier particle such as microspheres, nanoparticles, liposomes, etc which modulates the release and absorption characteristics of the drug. Among these drug delivery system we are selecting microspheres of various types which will be controlled release and which can be made specific site targeted by giving some specific characteristic to it like mucoadhesion character or by inserting any magnetic or radioactive material as a result of which it will show site specific action. So this article emphasis on different types of microspheres as a controlled and targeted drug delivery system.

Keywords: Microsphere, target site, Specificity, controlled release.


[Full Text Article]

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