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Abstract

A REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF OLANZAPINE AND SERTRALINE HYDROCHLORIDE

Nidhi S. Ghetiya and Dr. Dilip G. Maheshwari*

ABSTRACT

Olanzapine and Sertraline are effective in ameliorating symptoms of depression, anxiety and aggression, reducing sensitivity in interpersonal relationships and alleviating obsessive symptoms, pessimistic behaviors and somatization disorders in patients with personality disorders on methadone maintenance therapy. They are generally administered as tablet. This review entails different methods developed for determination of the combination of Olanzapine and Sertraline Hydrochloride like UV-spectroscopy and HPLC method.

Keywords: Olanzapine, Sertraline Hydrochloride, UV-Spectroscopy, High Performance Liquid Chromatography (HPLC).


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