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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2025 Issue has been successfully launched on 1 NOVEMBER 2025.

Abstract

GREEN BIOSYNTHESIS OF SILVER NANOPARTICLES FROM ELETTARIA CARDAMOMUM (SEED) AND ITS IN VITRO CYTOTOXIC ACTIVITY

Venugopal Krishnan*1, Rajagopal Kalyanaraman, Gracy Fathima, Khalefathullah Sheriff, Mohamed Illiyas, Hilal Ahmad Rather, Ramar Thangam2and Thenmozhi
Krishnan

ABSTRACT

The green synthesis of silver nanoparticles (AgNPs) using Elettaria cardamomum (seed) extract and its cytotoxicity activity against Hep-2 cell line were reported. The synthesized AgNPs using Elettaria cardamomum extract was preliminarily confirmed by UV– visible spectroscopy and it was further characterized by FT-IR. The UV–visible spectrum showed an absorption peak at 456 nm which reflects surface plasmon resonance (SPR) of AgNP. the green synthesized AgNPs exhibited a dose-dependent cytotoxicity against Human Larynx Carcinoma cancer(Hep-2) and the inhibitory concentration (IC50) were found to be 51μg/ml. Furthermore, the synthesized SNPs shows significant anticancer activity against Hep-2 cancer cell line.

Keywords: Silver Nanoparticle, Anticancer, Elettaria cardamomum.

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