Abstract

SOLID LIPID NANOPARTICLES (SLN): APPROACH AND APPLICATIONS

Vinay Yadav*, AlokMahor, Dr.Sunil Prajapati, Shashi Alok and AmitaVerma

ABSTRACT

Solid lipid nanoparticles (SLN) have emerged as a next-generation drug delivery system with potential applications in pharmaceutical field, cosmetics, research, clinical medicine and other allied sciences. Recently, increasing attention has been focused on these SLN as colloidal drug carriers for incorporating hydrophilic or lipophilic drugs. Proteins and antigens intended for therapeutic purposes may be incorporated or adsorbed onto SLN, and further administered by parenteral routes or be alternative routes such as oral, nasal and pulmonary. Therefore SLNs is reaching the goal of controlled and site specific drug delivery system. In this article we discussed the preparation method, characterization, route of administration of SLNs, advantages, different preparation method which are suitable for large scale production and application of SLNs.

Keywords: Solid lipid nanoparticles (SLN).