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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2025 Issue has been successfully launched on 1 NOVEMBER 2025.

Abstract

DESIGN AND SYNTHESIS OF SOME NOVEL ISATIN CONTAINING ANALOGUES ANTI MICROBIAL PROPERTIES

Dr. M. Rajasekaran*, S. Rambalaji, S. Ranjitha, V. Punitha, V. Rajesh and P. Priyadharshini

ABSTRACT

This study involves the synthesis of two Isatin derivatives, characterized by their melting points (130-150°C) and analyzed using Thin Layer Chromatography (TLC) with a chloroform-methanol eluent (3:7 ratio). The solubility of the compounds was assessed in various solvents, with all showing good solubility in methanol, ethanol, DMSO, and DMF. The synthesized compounds were characterized by UV, IR, and 1H NMR spectroscopy. Biological activity screening revealed that both compounds exhibited antibacterial and antifungal properties, with Compound B demonstrating superior activity compared to Compound A.

Keywords: Isatin, Anti - Fungal, Anti – Bacterial.

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