Abstract

ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIES OF BOEHMERIA NIVEA (L.) GAUD

Tram Pham and Tu Nguyen*

ABSTRACT

Boehmeria nivea (L.) Gaud, has received limited research attention regarding its biological activities. This study aimed to evaluate the antibacterial and antioxidant properties of aqueous extracts from Boehmeria nivea (L.) Gaud, establishing its potential as a pharmaceutical candidate. Boehmeria nivea (L.) Gaud extracts obtained at room temperature (25°C), 60°C, and 95°C, named LGR, LG60, and LG95, respectively. The reducing power assay indicated that all three samples displayed increased absorbance with higher concentrations, signifying their antioxidant potential. Among the extracts, LG60 exhibited particularly effective antioxidant properties. In terms of antibacterial activity, all three extracts demonstrated significant inhibition against the Gram-negative bacteria (Pseudomonas aeruginosa ATCC 27853 and Klebsiella pneumoniae ATCC 13883) and the Gram-positive bacterium (Staphylococcus aureus ATCC 25923) but not inhibit Micrococcus luteus ATCC. The LGR extract exhibited the largest inhibition zone against P. aeruginosa with a diameter of 11.50 ± 0.0866 mm, while LG60 displayed the strongest inhibition against K. pneumoniae with a diameter of 11.50 ± 0.05 mm. These findings emphasize the potential of Boehmeria nivea (L.) Gaud as a valuable source of bioactive phytochemicals with antioxidant and antibacterial activities. The obtained information supports further research and the application of these compounds in various fields of life and science.

Keywords: Boehmeria nivea (L.) Gaud, antioxidant activity, antibacterial activity, different extracts.