Abstract

FORMULATION AND EVALUATION OF EFFERVESCENT GRANULES OF ARTEMISIA ARBORESCENCE HERBAL PRODUCT FOR FOODBORNE ILLNESS

Mahmoud Mahyoob Alburyhi* and Amina El-Shaibany

ABSTRACT

Artemisia arborescence plant widely distributed in Yemen, traditionally used to treat Dermatitis, allergic reactions, itchiness lymphatic drainage, venous congestions Asthma, hay fever, asthmatic bronchitis. The essential oil of this plant was traditionally used as an insect repellant, as flavourings and for fragrances. Inhalation of the oil is used to dilate and stimulate the bronchi, blood vessels of the heart and to stimulate the kidneys. The oil is for inhalation only. Artemisia arborescence has been used traditionally as an anti-inflammatory remedy. The essential oil of Artemisia arborescence has been reported to have antibacterial and antifungal activities as well as antiviral activity against HSV-1 and HSV-2. Artemisia arborescence essential oil also exhibited antifungal activity against Cladosporium cucumerinum. The cytotoxic activity of Artemisia arborescence can be attributed to the presence of α-bisabolol and palmitic acid. Artemisia arborescence is commonly used in traditional medicine for a wide range of ailments including gastritis and gastric ulcer. Food poisoning commonly caused by salmonella typhimurium pathogenic gram- negative short rods. For food poisoning of ethanol extract of Artemisia arborescence was evaluated at the dose of 250mg/kg and showed a significant activity. Artemisia arborescence was formulated as effervescent granules and evaluate for organoleptic properties of ethanol extract of Artemisia arborescence. The results show that the extract was sparingly soluble, excellent flowability of extract powder, the best formula of effervescent granules is F3 showed the best result in dissolution was 100% after 5min.

Keywords: Artemisia arborescence, Extract, Effervescent granules, Herbal Medicines.