World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , Indian Science Publications , SOCOLAR, China , NewJour-Georgetown University Library, USA , eGranary Digital Library, USA , CAS (A Division of American Chemical Society) USA , VIKAS PSOAR (Pharmaceutical Sciences Open Access Resources) , Urlich's Periodicals Directory, Proquest, UK , AYUSH RESEARCH PORTAL , Scopus ((Elsevier Products in process) , EMBASE (Elsevier Products, in process) , EBSCO Publishing Inc (Academic Search Complete, USA, In Process) , Genamics JournalSeek (In Process) , Kaohsiung Medical University Library (In Process) , OurGlocal (In Process) , eSci Research, International Research Organization. , Geneva Foundation for Medical Education and Research, Switzerland (In Process) , Thomson Reuters, USA (in process) , Polish Scholarly Bibliography , Virtual Library Pharmacy, Medicine and Health, Biosciences , Global Impact Factor (0.629) , UDLedge Science Citation Index , International Impact Factor Services , Directory of Research Journal Indexing (DRJI) , Universal Impact Factor (1.0408) , International Scientific Indexing, UAE , SJIF - Scientific Journal Impact Factor (2.786) , Scholar Steer, (Under Process) , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , InfoBase Index (In Process) , Scholar Article Impact Factor, SAIF , Citations Impact (Under Process) , CiteFactor , Journal Index (JI, Under Process) , Indian citation Index (ICI) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Eurasian Scientific Journal Index (ESJI) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Journalseek Database , IP Indexing (IP Value 2.76) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , International Scientific Indexing ( ISI ) , Scope Database , Open Access Journal , Academia ,

World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

Login

Search

News & Updation

Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

Call for Paper

WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS: MAY ISSUE PUBLISHED

May Issue has been successfully launched on 1 May 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

CAN MONTELUKAST, THROUGH ITS ANTI-INFLAMMATORY AND AUTOPHAGY MODULATION CHARACTERISTICS, SHOW AN EFFECT ON TESTICULAR WEIGHT AND SPERM COUNT IN CAUDA EPIDIDYMIS?

Ahmed M. Awad*, Sally L. Elshaer, Rania R. Abdelaziz and Manar A. Nader

ABSTRACT

Hyperglycemia induces testicular atrophy and male infertility. We investigated the effect of cysteinyl leukotriene receptor (CysLTR)1 antagonism by montelukast on diabetes induced testicular complications. Streptozotocin (STZ, one dose 55 mg/kg)-induced diabetic (SD) rats were administered montelukast (10 and 20 mg/kg, orally) for 8 weeks. After that, both testicles from each animal were weighted and divided by the weight of animal. Sperms were also collected from cauda epididymis and were suspended in 2 ml normal saline at room temperature to be used immediately for sperm analysis. Montelukast showed protection against diabetes induced testicular atrophy, as evidenced by testicular weight index. On the other hand, it was unable to increase the sperm count in cauda epididymis at our time point of evaluation. The well-established antioxidant, anti-inflammatory, and autophagy stimulation characteristics of montelukast can explain its effect against diabetes induced testicular
atrophy.

Keywords: Montelukast, testicular atrophy, Sperms count.

[Download Article] [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Downloads

Author Instruction

Covering Letter

Copyright Form

Apycom jQuery Menus