Abstract

FORMULATION AND EVALUATION OF POLYHERBAL LOZENGES

Dr. G. N. Pramodini*, Marwa Riyaz, Syeda Shiza Fatima, Khan Matiur Rehman Habibur Rehman and Mohd. Abul Hasan Khan

ABSTRACT

The main objective of the study is to formulated and evaluate polyherbal lozenge remedy for suppressing cough for sore throat and cold the polyherbal extract based lozenge includes vasaka [Adhatoda vasica], ajwain [Trachyspermum ammi], mint tulsi [Ocimum tenuiflorum], ginger which are traditionally used for cough suppressant and in cold and flu and the other ingredients are honey and jaggery which are nutritive effect and soothing effect on the mucus membrane of the respiratory tract. The fresh leaf juices of all the ingredients were used for the preparation of polyherbal lozenges of both soft herbal lozenge and hard lozenge were prepared. Both the polyherbal lozenges were evaluated for their physicochemical parameters such as weight variation, thickness, hardness, moisture content, hardness friability, disintegration diameter were identified and there results were revealed as all the physicochemical parameter for both soft and hard lozenges were within the monograph standard which are mentioned in GMP Guidelines. The present research work was successfully concluded by taking feedback and responses from a hundred volunteers which includes both children and adults of either sex from the survey it was found that the polyherbal lozenges of both the types of soft and hard were effective in cough and sore throat conditions and with a acceptable taste. From the above investigations it was expertise to develop a polyherbal lozenge of both soft and hard herbal lozenges and it was just an attempt to make a polyherbal lozenges in which the leaves of mint tulsi and ajwain were incorporated for the first time and these polyherbal lozenges can be an effective, economical and easily available remedy for minor throat infections.

Keywords: Polyherbal lozenges, Vasaka, Ajwain, Mint tulsi, physio chemical.