Abstract

AG: C20H9CLO5AG AS A PLAUSIBLE PROMISING MATERIAL FOR THE TREATMENT OF DISEASE CONDITION OVER SARS COV-2

Savita D. Sonawane, Amarsingh V. Thakur, Pooja Suryawanshi, G. M. Vidyasagar, R. C. Ambare and Balkrishna J. Lokhande*

ABSTRACT

The severe acute respiratory syndrome coronavirus SARS-CoV-2 (2019-nCoV) is spreading a pandemic that has become a global disaster and is responsible for the death of over 1.5 lakh people around the world. There is no known vaccine to date over this pandemic. The medical practitioners are attempting the antibody therapies and the immunology therapies. The use of hydroxychloroquine is suggested for the time being as a cure but this too has been applied as a trial. The novel COVID 19 virus belongs to the family coronaviridae and shows a 75% resemblance with the other viruses such as alpha CoV, beta CoV, HCoV-OC43, HCoV-NL63, HCoV-229E,HCoV-HKU1, and MERS CoV. Ag nanoparticles have antiviral effects and have been proved effective in inhibiting HIV life cycle, inhibiting the RNA replication in HBV, antiviral effect over influenza, H1N1 flue, disease caused by H3N2. All these viruses belong to the family coronaviridae. Ag demonstrate enhanced virucidal effect when they are in the ionic state. So, Ag: C20H9ClO5Ag nanoparticles and Ag+ ions formed after reaction with the S, N, P, and O containing materials in the virus may exhibit the viricidal effects over the SARS-CoV-2 virus.

Keywords: Ag, Ag:C20H9ClO5Ag, Ag+ ions, SARS CoV-2.