Abstract

MICROSPHERES AS DRUG DELIVERY SYSTEM – A REVIEW

Smeeta S. Aher, Sumedha R. Dani* and Rishikesh S. Bacchav

ABSTRACT

Microspheres are the free flowing powders of proteins or synthetic polymers which are biodegradable in nature and having a particle size less than 200 μm. The therapeutic efficacy of microspheres containing drug is depend upon their characteristics which can be altered in required terms by alter the materials, methods, polymers or techniques used. The method of the preparation of microspheres providing multiple options to control as drug administration aspects and to enhance the therapeutic efficacy of a given the drug. Microspheres drug delivery systems offer various advantages compared to conventional dosage forms, which include improved efficacy, improved patient compliance, reduced toxicity and convenience. The aim of this review is to study various aspects of the microparticulate drug delivery system including method of prepration, evaluation, application & characterization microsphere.

Keywords: Microspheres, novel drug delivery, therapeutic efficacy, Controlled release.