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Abstract

LACOSAMIDE ESTIMATION IN BULK AND PHARMACEUTICAL DOSAGE FORM: A REVIEW

Shraddha Lasgare*, Ravindra Laware and Ganesh Shinde

ABSTRACT

Epilepsy is a central nervous system (neurological) disorder in which brain activity becomes abnormal, causing seizures or periods of surprising behaviour, sensations, and usually loss of awareness. Lacosamide (LCM) is a drug approved for the treatment of partial onset seizures. Lacosamide is used alone and in combination with other medication to control certain types of seizures. There are several analytical strategies including UV spectroscopy, HPLC and HPTLC reported for determination of lacosamide in bulk and its pharmaceutical dosage forms. The review focuses on validated UV and HPLC methods for lacosamide estimation.

Keywords: .


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