Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS JANUARY ISSUE PUBLISHED
  • JANUARY 2021 Issue has been successfully launched on 1 January 2021.

Abstract

REMDESIVIR FOR COVID-19: A REVIEW

Anjali Shivaji Shilimkar**

ABSTRACT

In the global pandemic of novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Remdesivir as a drug captured serious worldwide attention. Basically it is nucleoside analogue prodrug, its unique structural features allow high concentration of the active triphosphate metabolite to be delivered intracellularly. Some in vivo and in vitro studies show inhibition of SARS-CoV-2 by the use of remdesivir. The clinical trial of remdesivir is still in progress therefore the further proof to prove remdesivir’s efficacy against COVID-19 is of considerable international concern. Here, I provide an overview of remdesivir’s mechanism of action, clinical usage, in vivo and in vitro studies. Finally, considering the public health and pharmacovigilance approach is also discussed.

Keywords: Remdesivir, COVID-19, SARS-CoV-2, RNA dependent RNA polymerase, GS- 441524.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More